Last edited by Daramar
Monday, July 20, 2020 | History

1 edition of Alpha interferon found to be effective treatment for chronic hepatitis C found in the catalog.

Alpha interferon found to be effective treatment for chronic hepatitis C

Alpha interferon found to be effective treatment for chronic hepatitis C

  • 248 Want to read
  • 34 Currently reading

Published by National Institutes of Health in Bethesda, Md .
Written in English

    Subjects:
  • Hepatitis -- Treatment -- United States

  • Edition Notes

    SeriesThe Search for health, Search for health
    ContributionsNational Institute of Health (U.S.)
    The Physical Object
    Pagination[1] leaf ;
    ID Numbers
    Open LibraryOL14654272M

    Antiviral therapy with peginterferon plus ribavirin in treatment-naïve patients with chronic hepatitis C was the most effective ( life years gained [LYG]) treatment and was reasonably cost-effective (cost-saving to 84 ∈/quality adjusted life years [QALY]) when compared to interferon plus ribavirin. Objectives: The authors described a case of Hashimoto's disease during interferon-alpha (IFN-alpha) treatment for chronic viral C hepatitis in a patient with the specific genetic susceptibility associated with the thyroid disease. Results: A year-old woman with chronic active viral C hepatitis (HCV genotype = 3a) started IFN-alpha therapy in November '

    A selective one-time HCV screening program for people or years of age in Canada would likely be cost-effective. Identification of silent cases of chronic HCV infection and the offer of treatment when appropriate could extend the lives of Canadians at reasonable cost. Interferon alfacon-1 exhibits 88% similarity to human interferon-α2 and 70% similarity to human interferon-β based on an amino acid sequence comparison. Infergen is approved in the United States for the treatment of chronic hepatitis C infection in individuals with compensated liver disease.

    Early reports from Russia using intranasal interferon indicated that it could be an effective prophylaxis and treatment. 10, 11 Follow‐up studies conducted elsewhere found minimal benefits and unacceptable side effects when high‐dose intranasal IFN (>10 6 International Units, IU) was used. Intranasal IFN prophylaxis has been shown to. * Some patients with chronic hepatitis C virus infection do not respond to initial treatment with pegylated interferon plus ribavirin.. Contribution * This randomized trial compared peginterferon-{alpha}2a plus ribavirin for either 48 or 72 weeks in adults with hepatitis C who had not responded to peginterferon-{alpha}2b plus ribavirin.


Share this book
You might also like
Harpers Weekly April 19, 1862

Harpers Weekly April 19, 1862

Semantics

Semantics

Under the magnifying glass

Under the magnifying glass

Engineering Heritage

Engineering Heritage

Proceedings of the First National Seminar on Victims Rights and the Judicial Process, Toronto, Ontario, February 10-12, 1985

Proceedings of the First National Seminar on Victims Rights and the Judicial Process, Toronto, Ontario, February 10-12, 1985

French

French

Californias spiritual frontiers

Californias spiritual frontiers

Accounting and disclosure requirements of the Companies Act 1981

Accounting and disclosure requirements of the Companies Act 1981

Vibrational-rotational spectroscopy for planetary atmospheres

Vibrational-rotational spectroscopy for planetary atmospheres

The narcotic laws of Mexico and the United States of America.

The narcotic laws of Mexico and the United States of America.

Accuracy of titles in describing content of biological sciences articles

Accuracy of titles in describing content of biological sciences articles

Edgar Allan Poe.

Edgar Allan Poe.

Light To The Heart (Light to the Heart)

Light To The Heart (Light to the Heart)

Ecce venit =

Ecce venit =

Concrete in highway engineering

Concrete in highway engineering

Oscar Wilde

Oscar Wilde

Alpha interferon found to be effective treatment for chronic hepatitis C Download PDF EPUB FB2

Interferon alfa-2b is used to treat hairy cell leukemia, malignant melanoma, follicular lymphoma, Kaposi's sarcoma caused by AIDS, and certain types of genital eron alfa-2b is also used to treat chronic hepatitis B or C in adults, and to treat chronic hepatitis B in children who are at least 1 year name: Intron A.

Interferon is the drug of choice for treating several chronic forms of viral hepatitis, including hepatitis B and C. It may also be used to treat a more unusual type of hepatitis called hepatitis.

Alpha interferons have been used widely to treat chronic hepatitis C virus infection. These include recombinant interferons, purified natural leukocyte, and lymphoblastoid interferons.

Alpha interferon is administered by subcutaneous or intramuscular injection either daily or three times weekly for a period of 6 to as long as 24 by:   Interferon treatment for hepatitis C would typically last 24–48 weeks (6–12 months). Interferons caused many long-term side effects partly because of this long treatment time.

We studied the antiviral effectiveness and safety of interferon alfa‐n3, a natural alpha interferon which contains multiple interferon species, in the treatment of previously untreated patients with chronic hepatitis C.

Seventy‐seven patients were randomized to receive either,or million units (MU) of interferon alfa‐n3 three times a week for 24 weeks and were then Cited by: When used with the antiviral drug ribavirin, PEGylated interferon is effective in treatment of hepatitis C; at least 75% of people with hepatitis C genotypes 2 or 3 benefit from interferon treatment, although this is effective in less than 50% of people infected with genotype 1 (the more common form of hepatitis C virus in both the U.S.

and. To Fish, either interferon-alfa or -beta could be effective in managing COVID But, she argued, researchers should focus on studying the drugs as. Introduction. Chronic hepatitis C virus (HCV) infection has caused an epidemic with approximately million people infected worldwide and three to four million people newly infected each year.

1, 2 The majority of newly infected individuals develop chronic infection. Natural history studies show that 5% to 20% of patients develop cirrhosis after about 20 years of infection. 3 An. In the early s, when only hepatitis types A and B were recognized, treatment was focused on the acute illness and consisted of strict bed rest, a nutritious diet, and the judicious use of medications.

1, 2 Corticosteroid treatment was attempted and reduced serum bilirubin levels, but it probably promoted the evolution of acute hepatitis B to chronic hepatitis B. 3, 4 The search for drugs. This treatment is for adults with chronic hepatitis C genotypes 1 through 6, and treatment duration can be as little as eight weeks.

Results. "We proposed that therapy combining [Lescol] with alpha interferon may be effective for the treatment of patients with chronic hepatitis C," Ikeda and colleagues write.

They suggest a triple. Interferon has been shown to be effective in the treatment of chronic hepatitis C but the optimal treatment regime has not yet been defined. Studies using 3 million units (MU) of interferon thrice weekly (tiw) for 6 months have shown normalization of serum alanine aminotransferase (ALT) in about 50% of patients, but relapse occurs in at least 50% of responders after interferon is stopped.

The first pharmacological regimen for hepatitis C was introduced in the s and consisted of non-pegylated interferon alpha-2a or alpha-2b mono-therapy. The treatment duration was 24 or 48 weeks, depending on the hepatitis C genotype, and required thrice weekly injections.[ 9 ].

Abstract. Interferon–α (IFN-α) has been indicated to be dramatically effective in some but not all patients with chronic hepatitis C. We investigated retrospectively our patients treated with IFN-α for a better regimen of the therapy and for any effective predictors of responsiveness to the treatment.

The Future of Hepatitis C Therapy. With such high rates of success with current treatments, it may seem like the hepatitis C story is in its final chapters, but it is not over yet. A vaccine against hepatitis C would cause the prevalence of the disease to plummet, but efforts to produce a vaccine, while still under way, have not yet been.

Uses: For the treatment of chronic hepatitis C in patients with compensated liver disease who have history of blood or blood-product exposure and/or are HCV antibody positive; in combination with ribavirin, for the treatment of chronic hepatitis C in patients with compensated liver disease previously untreated with alpha interferon therapy and.

The global interferon drugs market is projected to grow at a rapid pace in the next few years because of advanced method of treatment. Increase in incidence of chronic diseases such as hepatitis. Summary To evaluate the effect and side‐effects of alpha interferon 2B (IFN) treatment in haemophilia patients with chronic hepatitis C (positive HCV antibody test, positive HCV‐RNA test and ALT le.

Bonkovsky HL, Clifford BD, Smith LJ, Allan C, Banner B. High-dose interferon-a2b for re-treatment of nonresponders or relapsing patients with chronic hepatitis C-a controlled randomized trial. Dig Dis Sci ; Iino S.

High dose interferon treatment in chronic hepatitis C. Get this from a library. Alpha interferon found to be effective treatment for chronic hepatitis C. [National Institute of Health (U.S.);].

interferon alfa-2b is approved for the treatment of hairy cell leukemia, malignant melanoma, condylomata acuminata, AIDS-related Kaposi's sarcoma, chronic hepatitis C, and chronic hepatitis B.

Ribavirin combined with interferon alfa-2b, interferon alfacon-1 (Infergen), pegylated interferon alfa-2b, or pegylated interferon alpha-2a, all are.Hepatitis C virus infection is a common disease with a high propensity to progress towards chronicity. Alpha interferon has been proposed to halt progression of the disease and prevent the development of more severe liver diseases such as cirrhosis and hepatocellular carcinoma.Hepatitis C is a liver disease caused by the hepatitis C virus (HCV).

It is the most common chronic bloodborne infection in the United States. Some of those infected with hepatitis C are able to clear the virus from their blood within about 6 months from the time of infection. However, about 75% of people .